- accession:NM_003991
- 基因别名:EDNRB
- 基因描述:Homo sapiens endothelin receptor type B (EDNRB), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1311
- 翻译后氨基酸长度:436
- TranscriptVariant:This variant (2) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
- 基因简介:The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
- 规格:10ul 质粒
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