- accession:NM_001436
- 基因别名:FBL
- 基因描述:Homo sapiens fibrillarin (FBL), mRNA.
- 载体:现货载体
- CDS区长度:966
- 翻译后氨基酸长度:321
- 基因简介:This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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