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人 OBSCN (NM_001271223) cDNA克隆
人 OBSCN (NM_001271223) cDNA克隆
  • 商品货号:FC123860
  • 已售 5 件 | 评价 0 人次 | 关注度 346
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    • accession:NM_001271223
    • 基因别名:OBSCN
    • 基因描述:Homo sapiens obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), transcript variant IC, mRNA.
    • 载体:现货载体
    • CDS区长度:26772
    • 翻译后氨基酸长度:8923
    • TranscriptVariant:This variant (IC) represents an inferred complete model that includes additional in-frame coding exons with consensus splice sites. The exons included in this inferred variant are supported by a combination of available cDNA data and sequence analysis of repetitive exons. This transcript represents a predicted protein (isoform IC) of 8,923 amino acids.
    • 基因简介:The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列