- accession:NM_021233
- 基因别名:DNASE2B
- 基因描述:Homo sapiens deoxyribonuclease II beta (DNASE2B), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1086
- 翻译后氨基酸长度:361
- TranscriptVariant:This variant (1) is the full-length transcript and encodes the longer isoform (1), which is more highly expressed in the salivary gland.
- 基因简介:The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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