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- accession：NM_004946
- 基因别名：DOCK2
- 基因描述：Homo sapiens dedicator of cytokinesis 2 (DOCK2), mRNA.
- 载体：现货载体
- CDS区长度：5493
- 翻译后氨基酸长度：1830
- 基因简介：The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection. [provided by RefSeq, Oct 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列ATGGCCCCCTGGCGCAAAGCTGACAAGGAGCGGCACGGCGTGGCCATATACAACTTCCAAGGCAGCGGAG
CCCCCCAGCTCTCCCTGCAGATCGGCGATGTGGTGCGAATACAGGAGACGTGTGGAGACTGGTATAGGGG
ATACCTCATAAAGCACAAAATGTTACAGGGCATTTTTCCTAAGTCATTTATCCACATCAAGGAAGTGACA
GTTGAGAAAAGAAGAAATACTGAGAACATCATTCCTGCAGAAATTCCTCTGGCACAAGAAGTGACAACGA
CACTTTGGGAATGGGGAAGCATCTGGAAACAACTCTATGTGGCCAGCAAAAAGGAGCGTTTTCTCCAGGT
GCAGTCCATGATGTACGATCTGATGGAGTGGAGGTCCCAGCTTCTCTCAGGAACCTTACCCAAGGATGAG
CTGAAGGAACTGAAGCAGAAAGTCACGTCCAAAATTGACTATGGCAACAAAATCCTTGAGCTTGATTTGA
TTGTCAGAGATGAAGACGGAAATATCTTGGACCCTGATAATACCAGTGTCATCAGCTTGTTCCATGCACA
TGAGGAAGCAACTGATAAAATCACAGAGCGTATCAAAGAAGAAATGTCAAAAGACCAGCCAGATTATGCA
ATGTATTCCCGGATCTCCTCATCCCCCACCCATAGCCTCTATGTGTTTGTGAGAAACTTTGTGTGCAGAA
TTGGGGAAGATGCTGAGCTCTTCATGTCTCTCTACGACCCCAACAAGCAAACGGTCATAAGTGAGAACTA
CCTAGTGCGATGGGGCAGCCGGGGCTTCCCTAAGGAGATTGAGATGCTCAACAATCTGAAGGTGGTCTTC
ACGGATCTTGGAAACAAAGACCTCAACAGGGATAAAATTTACTTGATTTGTCAAATAGTCCGGGTCGGCA
AGATGGATCTTAAGGATACTGGTGCAAAGAAGTGCACGCAGGGACTGAGGAGGCCCTTTGGGGTGGCAGT
TATGGATATAACAGACATCATCAAGGGGAAAGCAGAGAGTGATGAAGAAAAGCAGCACTTCATTCCTTTT
CACCCGGTTACAGCTGAGAATGACTTCCTACACAGCCTGCTGGGCAAAGTCATAGCCTCCAAGGGGGACA
GTGGAGGGCAAGGCCTCTGGGTGACCATGAAGATGCTGGTGGGTGACATCATTCAGATTCGCAAGGACTA
TCCACACCTGGTGGACAGGACCACCGTGGTGGCCAGGAAGCTGGGATTCCCAGAGATCATCATGCCAGGG
GATGTCAGGAACGACATCTACATTACTCTCTTACAAGGTGACTTTGACAAGTACAACAAGACCACACAGA
GGAATGTGGAAGTCATCATGTGTGTGTGCGCGGAGGATGGCAAAACGCTGCCTAATGCAATTTGCGTGGG
AGCAGGGGACAAGCCCATGAATGAGTATCGCTCCGTTGTGTACTATCAAGTCAAACAGCCACGCTGGATG
GAAACAGTCAAGGTGGCTGTCCCTATTGAAGACATGCAGAGGATCCATCTGCGATTCATGTTTCGACATC
GGTCATCTCTGGAATCTAAAGATAAAGGAGAAAAGAACTTTGCCATGTCCTATGTGAAGCTGATGAAAGA
AGATGGGACTACTCTACACGATGGATTCCATGACTTAGTTGTCCTCAAGGGGGACAGCAAGAAGATGGAG
GATGCCAGCGCATACCTGACCCTTCCTTCTTATCGACACCATGTGGAAAACAAGGGGGCCACGCTGAGCA
GGAGCTCCAGCAGTGTTGGGGGGCTTTCTGTCAGCTCCCGGGATGTGTTCTCCATTTCCACCCTGGTGTG
CTCCACAAAGCTCACTCAGAATGTGGGCTTGCTGGGTTTGCTGAAGTGGCGTATGAAGCCTCAACTGCTA
CAGGAGAATTTAGAAAAGTTGAAGATTGTGGATGGAGAGGAAGTGGTGAAGTTTCTCCAGGATACTCTGG
ATGCCCTCTTCAACATCATGATGGAGCATTCTCAAAGTGATGAATATGACATCCTCGTCTTTGATGCCTT
GATTTACATAATAGGACTCATTGCAGACCGGAAATTTCAGCATTTCAACACCGTTCTGGAGGCTTACATC
CAACAGCATTTCAGTGCGACCTTGGCTTACAAGAAATTGATGACAGTGCTGAAGACTTACTTGGATACCT
CCAGCAGAGGGGAGCAATGTGAGCCAATCCTAAGAACGCTGAAGGCTTTGGAATATGTGTTCAAGTTCAT
TGTTCGGTCGAGGACATTATTTTCACAGCTTTATGAAGGCAAAGAACAGATGGAGTTTGAAGAATCCATG
AGACGGCTCTTTGAATCCATCAACAATCTGATGAAAAGTCAATACAAAACTACCATCCTTTTGCAGGTGG
CGGCTTTGAAATACATCCCATCTGTCCTGCATGATGTAGAAATGGTCTTTGATGCGAAGTTACTCAGCCA
ACTCCTGTATGAGTTCTACACCTGCATCCCTCCTGTGAAACTCCAGAAGCAGAAAGTACAGTCTATGAAT
GAGATAGTCCAGAGCAACCTCTTTAAAAAGCAAGAATGCCGGGACATTCTGCTTCCTGTCATCACCAAAG
AGCTGAAGGAGCTGCTGGAGCAGAAGGATGACATGCAACACCAGGTCCTGGAGAGGAAGTACTGCGTTGA
ATTGCTCAACAGCATCTTGGAAGTCCTTAGCTACCAGGATGCGGCCTTCACCTACCACCATATCCAGGAG
ATCATGGTCCAGCTGCTGCGGACAGTGAACCGGACAGTCATCACCATGGGCCGGGATCACATTCTGATTA
GTCACTTTGTGGCATGTATGACAGCCATCTTAAACCAGATGGGTGACCAGCACTACTCCTTCTACATTGA
GACCTTCCAGACCAGCTCTGAACTTGTGGACTTCTTGATGGAGACCTTCATCATGTTCAAGGACCTCATT
GGAAAGAACGTGTACCCTGGAGACTGGATGGCCATGAGCATGGTTCAAAACAGGGTCTTCCTGAGAGCTA
TCAACAAGTTTGCAGAAACCATGAACCAGAAGTTCCTAGAACACACGAACTTTGAGTTCCAGCTGTGGAA
CAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGAGCAGTTCTCACACGCC
AAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGT
GGTACAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACT
TATCCCTGAGGCTGAGCTCCGGAAAGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAA
AGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAAGCTGGACCACGAGGTAGAAGGGGGCC
GAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCCAACCAT
TGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGT
GTGATGACAGATGAGAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATA
ACAACAGGGAGGAGATGTACATAAGGTACCTGTACAAACTCCGCGATCTTCACCTGGACTGTGACAATTA
CACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGATGAGCAGTGTGCATCA
CAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCA
TCATAGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACA
GTACGAGATGGAGATCTTTGACTATGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAA
AGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGTTGGATACTACGGCCAGGGATTCCCCT
CCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCAGATGCA
GCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAAT
GCCCCAGGCCAGTATATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATA
AGCCAGTGCCTGACCAGATTATAAACTTCTACAAATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCC
CGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGAGAGAACCTCCTTCGTG
ACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTC
CTCTGGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCA
GAGTGATGAGACCCTCCCCATCAACCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATG
GGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTATGTCAGGGACCACCCTGAGGACCAGG
ACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAAGATCCA
TGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAA
ATGAAGGTGGAGAAGGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCA
GGTCTATGCTGCGCTCATACAGACAGATGTCCATCATCTCTCTGGCTTCCATGAATTCTGACTGCAGCAC
CCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGACGCCGAGAGTGGAGCAG
GAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGA
GAAGCAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCA
TGAGTTCATGAGTGACACCAACCTCTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAA
ATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGCGCTCTCAGTGGCAGGCATCCCTGGGT
TGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAAGAAGAC
ACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAA
CAGATCCCAGACTCGCTGTCCACGGACCTGTGA翻译后氨基酸参数序列： 点击查看序列ATGGCCCCCTGGCGCAAAGCTGACAAGGAGCGGCACGGCGTGGCCATATACAACTTCCAAGGCAGCGGAG
CCCCCCAGCTCTCCCTGCAGATCGGCGATGTGGTGCGAATACAGGAGACGTGTGGAGACTGGTATAGGGG
ATACCTCATAAAGCACAAAATGTTACAGGGCATTTTTCCTAAGTCATTTATCCACATCAAGGAAGTGACA
GTTGAGAAAAGAAGAAATACTGAGAACATCATTCCTGCAGAAATTCCTCTGGCACAAGAAGTGACAACGA
CACTTTGGGAATGGGGAAGCATCTGGAAACAACTCTATGTGGCCAGCAAAAAGGAGCGTTTTCTCCAGGT
GCAGTCCATGATGTACGATCTGATGGAGTGGAGGTCCCAGCTTCTCTCAGGAACCTTACCCAAGGATGAG
CTGAAGGAACTGAAGCAGAAAGTCACGTCCAAAATTGACTATGGCAACAAAATCCTTGAGCTTGATTTGA
TTGTCAGAGATGAAGACGGAAATATCTTGGACCCTGATAATACCAGTGTCATCAGCTTGTTCCATGCACA
TGAGGAAGCAACTGATAAAATCACAGAGCGTATCAAAGAAGAAATGTCAAAAGACCAGCCAGATTATGCA
ATGTATTCCCGGATCTCCTCATCCCCCACCCATAGCCTCTATGTGTTTGTGAGAAACTTTGTGTGCAGAA
TTGGGGAAGATGCTGAGCTCTTCATGTCTCTCTACGACCCCAACAAGCAAACGGTCATAAGTGAGAACTA
CCTAGTGCGATGGGGCAGCCGGGGCTTCCCTAAGGAGATTGAGATGCTCAACAATCTGAAGGTGGTCTTC
ACGGATCTTGGAAACAAAGACCTCAACAGGGATAAAATTTACTTGATTTGTCAAATAGTCCGGGTCGGCA
AGATGGATCTTAAGGATACTGGTGCAAAGAAGTGCACGCAGGGACTGAGGAGGCCCTTTGGGGTGGCAGT
TATGGATATAACAGACATCATCAAGGGGAAAGCAGAGAGTGATGAAGAAAAGCAGCACTTCATTCCTTTT
CACCCGGTTACAGCTGAGAATGACTTCCTACACAGCCTGCTGGGCAAAGTCATAGCCTCCAAGGGGGACA
GTGGAGGGCAAGGCCTCTGGGTGACCATGAAGATGCTGGTGGGTGACATCATTCAGATTCGCAAGGACTA
TCCACACCTGGTGGACAGGACCACCGTGGTGGCCAGGAAGCTGGGATTCCCAGAGATCATCATGCCAGGG
GATGTCAGGAACGACATCTACATTACTCTCTTACAAGGTGACTTTGACAAGTACAACAAGACCACACAGA
GGAATGTGGAAGTCATCATGTGTGTGTGCGCGGAGGATGGCAAAACGCTGCCTAATGCAATTTGCGTGGG
AGCAGGGGACAAGCCCATGAATGAGTATCGCTCCGTTGTGTACTATCAAGTCAAACAGCCACGCTGGATG
GAAACAGTCAAGGTGGCTGTCCCTATTGAAGACATGCAGAGGATCCATCTGCGATTCATGTTTCGACATC
GGTCATCTCTGGAATCTAAAGATAAAGGAGAAAAGAACTTTGCCATGTCCTATGTGAAGCTGATGAAAGA
AGATGGGACTACTCTACACGATGGATTCCATGACTTAGTTGTCCTCAAGGGGGACAGCAAGAAGATGGAG
GATGCCAGCGCATACCTGACCCTTCCTTCTTATCGACACCATGTGGAAAACAAGGGGGCCACGCTGAGCA
GGAGCTCCAGCAGTGTTGGGGGGCTTTCTGTCAGCTCCCGGGATGTGTTCTCCATTTCCACCCTGGTGTG
CTCCACAAAGCTCACTCAGAATGTGGGCTTGCTGGGTTTGCTGAAGTGGCGTATGAAGCCTCAACTGCTA
CAGGAGAATTTAGAAAAGTTGAAGATTGTGGATGGAGAGGAAGTGGTGAAGTTTCTCCAGGATACTCTGG
ATGCCCTCTTCAACATCATGATGGAGCATTCTCAAAGTGATGAATATGACATCCTCGTCTTTGATGCCTT
GATTTACATAATAGGACTCATTGCAGACCGGAAATTTCAGCATTTCAACACCGTTCTGGAGGCTTACATC
CAACAGCATTTCAGTGCGACCTTGGCTTACAAGAAATTGATGACAGTGCTGAAGACTTACTTGGATACCT
CCAGCAGAGGGGAGCAATGTGAGCCAATCCTAAGAACGCTGAAGGCTTTGGAATATGTGTTCAAGTTCAT
TGTTCGGTCGAGGACATTATTTTCACAGCTTTATGAAGGCAAAGAACAGATGGAGTTTGAAGAATCCATG
AGACGGCTCTTTGAATCCATCAACAATCTGATGAAAAGTCAATACAAAACTACCATCCTTTTGCAGGTGG
CGGCTTTGAAATACATCCCATCTGTCCTGCATGATGTAGAAATGGTCTTTGATGCGAAGTTACTCAGCCA
ACTCCTGTATGAGTTCTACACCTGCATCCCTCCTGTGAAACTCCAGAAGCAGAAAGTACAGTCTATGAAT
GAGATAGTCCAGAGCAACCTCTTTAAAAAGCAAGAATGCCGGGACATTCTGCTTCCTGTCATCACCAAAG
AGCTGAAGGAGCTGCTGGAGCAGAAGGATGACATGCAACACCAGGTCCTGGAGAGGAAGTACTGCGTTGA
ATTGCTCAACAGCATCTTGGAAGTCCTTAGCTACCAGGATGCGGCCTTCACCTACCACCATATCCAGGAG
ATCATGGTCCAGCTGCTGCGGACAGTGAACCGGACAGTCATCACCATGGGCCGGGATCACATTCTGATTA
GTCACTTTGTGGCATGTATGACAGCCATCTTAAACCAGATGGGTGACCAGCACTACTCCTTCTACATTGA
GACCTTCCAGACCAGCTCTGAACTTGTGGACTTCTTGATGGAGACCTTCATCATGTTCAAGGACCTCATT
GGAAAGAACGTGTACCCTGGAGACTGGATGGCCATGAGCATGGTTCAAAACAGGGTCTTCCTGAGAGCTA
TCAACAAGTTTGCAGAAACCATGAACCAGAAGTTCCTAGAACACACGAACTTTGAGTTCCAGCTGTGGAA
CAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGAGCAGTTCTCACACGCC
AAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGT
GGTACAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACT
TATCCCTGAGGCTGAGCTCCGGAAAGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAA
AGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAAGCTGGACCACGAGGTAGAAGGGGGCC
GAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCCAACCAT
TGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGT
GTGATGACAGATGAGAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATA
ACAACAGGGAGGAGATGTACATAAGGTACCTGTACAAACTCCGCGATCTTCACCTGGACTGTGACAATTA
CACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGATGAGCAGTGTGCATCA
CAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCA
TCATAGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACA
GTACGAGATGGAGATCTTTGACTATGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAA
AGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGTTGGATACTACGGCCAGGGATTCCCCT
CCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCAGATGCA
GCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAAT
GCCCCAGGCCAGTATATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATA
AGCCAGTGCCTGACCAGATTATAAACTTCTACAAATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCC
CGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGAGAGAACCTCCTTCGTG
ACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTC
CTCTGGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCA
GAGTGATGAGACCCTCCCCATCAACCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATG
GGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTATGTCAGGGACCACCCTGAGGACCAGG
ACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAAGATCCA
TGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAA
ATGAAGGTGGAGAAGGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCA
GGTCTATGCTGCGCTCATACAGACAGATGTCCATCATCTCTCTGGCTTCCATGAATTCTGACTGCAGCAC
CCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGACGCCGAGAGTGGAGCAG
GAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGA
GAAGCAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCA
TGAGTTCATGAGTGACACCAACCTCTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAA
ATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGCGCTCTCAGTGGCAGGCATCCCTGGGT
TGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAAGAAGAC
ACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAA
CAGATCCCAGACTCGCTGTCCACGGACCTGTGA
