• accession：NM_015525
• 基因别名：IBTK
• 基因描述：Homo sapiens inhibitor of Bruton agammaglobulinemia tyrosine kinase (IBTK), mRNA.
• 载体：现货载体
• CDS区长度：4062
• 翻译后氨基酸长度：1353
• 基因简介：The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq, Jul 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGAGTTCACCCATGCCTGACTGCACATCAAAGTGTCGATCCCTGAAGCATGCTTTGGATGTCCTTTCTG
TGGTAACAAAGGGGAGCGAAAACCAGATTAAGGCCTTTCTCTCCAGTCATTGTTACAATGCTGCAACTAT
CAAGGATGTTTTTGGCAGGAATGCCCTCCACCTTGTTTCCTCCTGTGGAAAGAAAGGAGTGTTAGATTGG
CTTATTCAGAAAGGAGTGGATCTGTTGGTGAAAGACAAAGAGTCTGGATGGACAGCATTGCACAGAAGCA
TTTTTTATGGACATATTGATTGTGTTTGGTCTCTATTGAAGCATGGTGTTAGTCTGTATATTCAAGATAA
AGAAGGCTTGTCAGCTTTGGATCTTGTAATGAAGGATAGACCAACTCATGTAGTATTCAAGAATACTGAT
CCTACAGATGTTTATACTTGGGGCGATAATACAAATTTTACCCTGGGTCATGGAAGCCAGAATAGCAAAC
ATCATCCAGAGTTGGTGGATCTGTTCTCCAGGAGTGGGATTTATATCAAGCAGGTGGTGCTTTGTAAATT
TCACTCCGTGTTTCTGTCTCAGAAAGGGCAGGTTTATACCTGTGGTCATGGTCCTGGAGGGCGATTAGGA
CATGGAGATGAACAGACATGCTTGGTCCCTCGGCTTGTGGAAGGACTGAATGGTCATAATTGTTCCCAAG
TGGCAGCTGCTAAGGATCATACTGTTGTATTAACTGAAGATGGATGTGTTTATACATTTGGTCTAAACAT
TTTTCATCAATTAGGAATTATTCCACCGCCTTCCAGTTGTAATGTACCCAGACAGATACAGGCAAAATAT
CTGAAAGGAAGGACAATCATTGGCGTTGCAGCAGGCAGGTTTCATACAGTCCTATGGACTAGAGAAGCTG
TTTACACTATGGGACTAAATGGTGGACAACTGGGTTGTTTGCTAGATCCCAATGGAGAAAAGTGTGTAAC
TGCTCCTCGTCAGGTCTCTGCCCTTCACCATAAAGACATTGCTCTGTCTTTGGTTGCTGCAAGTGATGGA
GCTACAGTCTGTGTTACCACAAGGGGAGATATTTACTTACTTGCAGACTATCAGTGCAAGAAGATGGCTT
CTAAACAGTTGAACTTGAAAAAAGTTCTTGTGTCTGGGGGTCATATGGAATACAAGGTTGATCCTGAACA
TTTGAAAGAAAATGGGGGTCAAAAAATTTGCATTCTTGCAATGGATGGAGCTGGAAGGGTGTTTTGCTGG
AGATCAGTCAACAGTTCTCTGAAGCAGTGTCGATGGGCCTATCCACGTCAGGTCTTCATTTCTGATATTG
CTTTAAATAGAAATGAAATTCTATTTGTTACGCAAGATGGAGAAGGATTTAGAGGGAGATGGTTTGAAGA
GAAAAGAAAGAGTTCTGAAAAGAAAGAGATTTTATCAAACCTTCACAATTCCTCATCAGATGTGTCTTAT
GTCTCTGATATAAATAGTGTGTATGAAAGAATTCGACTTGAGAAACTTACCTTTGCACATAGAGCTGTTA
GTGTCAGCACAGATCCAAGTGGATGCAACTTTGCAATCCTGCAGTCAGATCCTAAAACAAGCCTTTATGA
AATTCCAGCTGTGTCCTCATCATCCTTTTTTGAAGAGTTTGGCAAACTGTTGAGGGAAGCAGATGAAATG
GACAGCATTCATGATGTGACATTTCAAGTTGGCAATAGACTCTTCCCTGCACATAAATATATTTTGGCAG
TGCATTCTGATTTTTTTCAGAAATTGTTTCTTTCAGATGGTAATACTTCAGAATTTACAGATATTTACCA
GAAAGATGAAGATTCTGCAGGGTGCCATCTCTTTGTGGTAGAGAAGGTTCATCCTGACATGTTTGAATAC
CTTTTACAATTTATATACACAGATACTTGTGACTTTTTAACTCATGGCTTCAAACCAAGAATACACTTAA
ACAAAAACCCAGAAGAATATCAGGGAACTCTGAATTCTCATTTGAATAAAGTGAATTTCCATGAAGATGA
TAACCAGAAGTCTGCATTTGAAGTTTACAAAAGTAATCAAGCTCAAACAGTTAGTGAGAGGCAGAAGAGC
AAACCTAAATCTTGTAAAAAAGGAAAAAATATTAGGGAAGATGATCCTGTAAGAATGTTGCAAACTGTTG
CAAAGAAATTCGACTTCAGTAATTTGAGTAGTAGGTTAGATGGAGTCAGATTTGAAAATGAAAAAATTAA
TGTTATTGCCAAGAACACTGGTAATAAACTGAAGCTAAGTCAGAAAAAATGTTCATTTCTGTGTGACGTG
ACCATGAAATCAGTGGATGGAAAGGAATTTCCTTGTCATAAATGTGTTCTTTGTGCTAGACTTGAATATT
TTCATAGTATGCTGAGTAGCTCATGGATTGAGGCTTCCAGTTGTGCAGCTCTGGAAATGCCAATACATTC
TGATATATTAAAAGTTATTTTGGACTACCTCTATACTGATGAAGCTGTGGTGATAAAAGAATCTCAAAAT
GTAGATTTTATTTGTAGTGTTCTTGTGGTGGCTGATCAACTTCTCATAACCCGGTTGAAAGAGATTTGTG
AAGTAGCATTAACTGAAAAACTTACCCTGAAGAATGCTGCTATGCTACTGGAATTTGCAGCAATGTATAG
TGCAAAACAGTTGAAACTGTCTTGTTTACAGTTTATAGGATTGAATATGGCAGCTTTACTTGAAGCAAGG
TCTCTTGATGTTTTAAGCGATGGTGTTTTGAAGGATCTTTCTGAGTTTTACCGGAAAATGATTCCAGCAA
TGGATAGAAGAGTCATTACACCATATCAAGATGGACCAGATATTAGCTATTTGGAAGTAGAAGATGGAGA
TATCTTCTTGAAAGAAGAAATAAATATGGAACAAAATCATTCGGAAACTATGTTCAAGAAAGCAAAAACA
AAAGCTAAAAAGAAGCCACGTAAACGTTCAGATAGTTCTGGAGGTTATAACCTTTCAGATATTATTCAGA
GTCCATCATCTACAGGATTATTAAAGTCTGGTAAGACCAATTCTGTGGAATCTCTTCCAGAACTGTTGAC
ATCAGACTCTGAAGGAAGCTATGCAGGAGTGGGTAGTCCTAGAGATTTACAGTCCCCTGATTTCACAACA
GGATTTCATTCAGATAAGATTGAGGCGAAAGTCAAACCGTATGTTAATGGTACATCTCCTGTGTATTCTA
GGGAAGATTTAAAACCATGGGAAAAGTCACCAATACTTAAAATATCTGCTCCACAGCCTATTCCCAGTAA
CAGAATTGATACTACCAGCTCTGCCAGTTGGGTTGCTGGTTCTTTCAGTCCTGTCAGCCCTCCTGTTGTG
GATCTCAGAACTATCATGGAAATAGAAGAAAGTAGACAAAAATGTGGAGCTACACCAAAGTCACATTTAG
GCAAAACAGTTTCTCATGGAGTTAAACTTTCTCAGAAGCAACGAAAAATGATTGCATTGACTACCAAGGA
AAACAATTCAGGAATGAATAGCATGGAAACAGTTTTATTCACTCCTTCAAAAGCCCCCAAACCAGTGAAT
GCATGGGCATCTTCTCTGCATTCAGTTTCATCCAAGTCATTCCGGGATTTCTTACTAGAAGAAAAAAAGT
CTGTTACTAGCCATAGTTCAGGCGATCATGTCAAAAAAGTTTCTTTTAAAGGAATTGAAAATTCTCAGGC
ACCAAAAATTGTCAGATGCTCTACCCATGGTACCCCAGGACCAGAAGGCAACCATATTTCAGATTTACCA
CTTCTAGACAGTCCCAATCCCTGGCTATCTTCTTCAGTGACTGCTCCATCCATGGTAGCCCCAGTCACTT
TTGCATCTATTGTAGAAGAAGAACTACAACAAGAAGCAGCTCTTATTAGAAGTCGAGAAAAACCGTTGGC
TCTGATTCAGATTGAGGAGCATGCCATACAAGATTTATTGGTTTTCTATGAGGCATTTGGCAACCCTGAA
GAGTTTGTCATTGTTGAAAGGACACCGCAGGGACCACTGGCAGTACCTATGTGGAATAAGCATGGATGCT
AG

翻译后氨基酸参数序列： 点击查看序列

ATGAGTTCACCCATGCCTGACTGCACATCAAAGTGTCGATCCCTGAAGCATGCTTTGGATGTCCTTTCTG
TGGTAACAAAGGGGAGCGAAAACCAGATTAAGGCCTTTCTCTCCAGTCATTGTTACAATGCTGCAACTAT
CAAGGATGTTTTTGGCAGGAATGCCCTCCACCTTGTTTCCTCCTGTGGAAAGAAAGGAGTGTTAGATTGG
CTTATTCAGAAAGGAGTGGATCTGTTGGTGAAAGACAAAGAGTCTGGATGGACAGCATTGCACAGAAGCA
TTTTTTATGGACATATTGATTGTGTTTGGTCTCTATTGAAGCATGGTGTTAGTCTGTATATTCAAGATAA
AGAAGGCTTGTCAGCTTTGGATCTTGTAATGAAGGATAGACCAACTCATGTAGTATTCAAGAATACTGAT
CCTACAGATGTTTATACTTGGGGCGATAATACAAATTTTACCCTGGGTCATGGAAGCCAGAATAGCAAAC
ATCATCCAGAGTTGGTGGATCTGTTCTCCAGGAGTGGGATTTATATCAAGCAGGTGGTGCTTTGTAAATT
TCACTCCGTGTTTCTGTCTCAGAAAGGGCAGGTTTATACCTGTGGTCATGGTCCTGGAGGGCGATTAGGA
CATGGAGATGAACAGACATGCTTGGTCCCTCGGCTTGTGGAAGGACTGAATGGTCATAATTGTTCCCAAG
TGGCAGCTGCTAAGGATCATACTGTTGTATTAACTGAAGATGGATGTGTTTATACATTTGGTCTAAACAT
TTTTCATCAATTAGGAATTATTCCACCGCCTTCCAGTTGTAATGTACCCAGACAGATACAGGCAAAATAT
CTGAAAGGAAGGACAATCATTGGCGTTGCAGCAGGCAGGTTTCATACAGTCCTATGGACTAGAGAAGCTG
TTTACACTATGGGACTAAATGGTGGACAACTGGGTTGTTTGCTAGATCCCAATGGAGAAAAGTGTGTAAC
TGCTCCTCGTCAGGTCTCTGCCCTTCACCATAAAGACATTGCTCTGTCTTTGGTTGCTGCAAGTGATGGA
GCTACAGTCTGTGTTACCACAAGGGGAGATATTTACTTACTTGCAGACTATCAGTGCAAGAAGATGGCTT
CTAAACAGTTGAACTTGAAAAAAGTTCTTGTGTCTGGGGGTCATATGGAATACAAGGTTGATCCTGAACA
TTTGAAAGAAAATGGGGGTCAAAAAATTTGCATTCTTGCAATGGATGGAGCTGGAAGGGTGTTTTGCTGG
AGATCAGTCAACAGTTCTCTGAAGCAGTGTCGATGGGCCTATCCACGTCAGGTCTTCATTTCTGATATTG
CTTTAAATAGAAATGAAATTCTATTTGTTACGCAAGATGGAGAAGGATTTAGAGGGAGATGGTTTGAAGA
GAAAAGAAAGAGTTCTGAAAAGAAAGAGATTTTATCAAACCTTCACAATTCCTCATCAGATGTGTCTTAT
GTCTCTGATATAAATAGTGTGTATGAAAGAATTCGACTTGAGAAACTTACCTTTGCACATAGAGCTGTTA
GTGTCAGCACAGATCCAAGTGGATGCAACTTTGCAATCCTGCAGTCAGATCCTAAAACAAGCCTTTATGA
AATTCCAGCTGTGTCCTCATCATCCTTTTTTGAAGAGTTTGGCAAACTGTTGAGGGAAGCAGATGAAATG
GACAGCATTCATGATGTGACATTTCAAGTTGGCAATAGACTCTTCCCTGCACATAAATATATTTTGGCAG
TGCATTCTGATTTTTTTCAGAAATTGTTTCTTTCAGATGGTAATACTTCAGAATTTACAGATATTTACCA
GAAAGATGAAGATTCTGCAGGGTGCCATCTCTTTGTGGTAGAGAAGGTTCATCCTGACATGTTTGAATAC
CTTTTACAATTTATATACACAGATACTTGTGACTTTTTAACTCATGGCTTCAAACCAAGAATACACTTAA
ACAAAAACCCAGAAGAATATCAGGGAACTCTGAATTCTCATTTGAATAAAGTGAATTTCCATGAAGATGA
TAACCAGAAGTCTGCATTTGAAGTTTACAAAAGTAATCAAGCTCAAACAGTTAGTGAGAGGCAGAAGAGC
AAACCTAAATCTTGTAAAAAAGGAAAAAATATTAGGGAAGATGATCCTGTAAGAATGTTGCAAACTGTTG
CAAAGAAATTCGACTTCAGTAATTTGAGTAGTAGGTTAGATGGAGTCAGATTTGAAAATGAAAAAATTAA
TGTTATTGCCAAGAACACTGGTAATAAACTGAAGCTAAGTCAGAAAAAATGTTCATTTCTGTGTGACGTG
ACCATGAAATCAGTGGATGGAAAGGAATTTCCTTGTCATAAATGTGTTCTTTGTGCTAGACTTGAATATT
TTCATAGTATGCTGAGTAGCTCATGGATTGAGGCTTCCAGTTGTGCAGCTCTGGAAATGCCAATACATTC
TGATATATTAAAAGTTATTTTGGACTACCTCTATACTGATGAAGCTGTGGTGATAAAAGAATCTCAAAAT
GTAGATTTTATTTGTAGTGTTCTTGTGGTGGCTGATCAACTTCTCATAACCCGGTTGAAAGAGATTTGTG
AAGTAGCATTAACTGAAAAACTTACCCTGAAGAATGCTGCTATGCTACTGGAATTTGCAGCAATGTATAG
TGCAAAACAGTTGAAACTGTCTTGTTTACAGTTTATAGGATTGAATATGGCAGCTTTACTTGAAGCAAGG
TCTCTTGATGTTTTAAGCGATGGTGTTTTGAAGGATCTTTCTGAGTTTTACCGGAAAATGATTCCAGCAA
TGGATAGAAGAGTCATTACACCATATCAAGATGGACCAGATATTAGCTATTTGGAAGTAGAAGATGGAGA
TATCTTCTTGAAAGAAGAAATAAATATGGAACAAAATCATTCGGAAACTATGTTCAAGAAAGCAAAAACA
AAAGCTAAAAAGAAGCCACGTAAACGTTCAGATAGTTCTGGAGGTTATAACCTTTCAGATATTATTCAGA
GTCCATCATCTACAGGATTATTAAAGTCTGGTAAGACCAATTCTGTGGAATCTCTTCCAGAACTGTTGAC
ATCAGACTCTGAAGGAAGCTATGCAGGAGTGGGTAGTCCTAGAGATTTACAGTCCCCTGATTTCACAACA
GGATTTCATTCAGATAAGATTGAGGCGAAAGTCAAACCGTATGTTAATGGTACATCTCCTGTGTATTCTA
GGGAAGATTTAAAACCATGGGAAAAGTCACCAATACTTAAAATATCTGCTCCACAGCCTATTCCCAGTAA
CAGAATTGATACTACCAGCTCTGCCAGTTGGGTTGCTGGTTCTTTCAGTCCTGTCAGCCCTCCTGTTGTG
GATCTCAGAACTATCATGGAAATAGAAGAAAGTAGACAAAAATGTGGAGCTACACCAAAGTCACATTTAG
GCAAAACAGTTTCTCATGGAGTTAAACTTTCTCAGAAGCAACGAAAAATGATTGCATTGACTACCAAGGA
AAACAATTCAGGAATGAATAGCATGGAAACAGTTTTATTCACTCCTTCAAAAGCCCCCAAACCAGTGAAT
GCATGGGCATCTTCTCTGCATTCAGTTTCATCCAAGTCATTCCGGGATTTCTTACTAGAAGAAAAAAAGT
CTGTTACTAGCCATAGTTCAGGCGATCATGTCAAAAAAGTTTCTTTTAAAGGAATTGAAAATTCTCAGGC
ACCAAAAATTGTCAGATGCTCTACCCATGGTACCCCAGGACCAGAAGGCAACCATATTTCAGATTTACCA
CTTCTAGACAGTCCCAATCCCTGGCTATCTTCTTCAGTGACTGCTCCATCCATGGTAGCCCCAGTCACTT
TTGCATCTATTGTAGAAGAAGAACTACAACAAGAAGCAGCTCTTATTAGAAGTCGAGAAAAACCGTTGGC
TCTGATTCAGATTGAGGAGCATGCCATACAAGATTTATTGGTTTTCTATGAGGCATTTGGCAACCCTGAA
GAGTTTGTCATTGTTGAAAGGACACCGCAGGGACCACTGGCAGTACCTATGTGGAATAAGCATGGATGCT
AG