- accession:NM_000921
- 基因别名:PDE3A
- 基因描述:Homo sapiens phosphodiesterase 3A, cGMP-inhibited (PDE3A), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:3426
- 翻译后氨基酸长度:1141
- TranscriptVariant:This variant (1) represents the longer transcript and encodes the longer isoform (1)
- 基因简介:This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
- 规格:10ul 质粒
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