- accession:NM_001256026
- 基因别名:ARHGAP22
- 基因描述:Homo sapiens Rho GTPase activating protein 22 (ARHGAP22), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:1827
- 翻译后氨基酸长度:608
- TranscriptVariant:This variant (4) differs in the 5' UTR and lacks a portion of the 5' coding region, uses an alternate in-frame splice site in a 5' exon, and initiates translation at an alternate start codon compared to variant 1. The resulting protein (isoform 4) is shorter and has a distinct N-terminus compared to isoform 1.
- 基因简介:This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
- 规格:10ul 质粒
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