- accession:NM_001199579
- 基因别名:SUN2
- 基因描述:Homo sapiens Sad1 and UNC84 domain containing 2 (SUN2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2217
- 翻译后氨基酸长度:738
- TranscriptVariant:This variant (1) represents the longest transcript and encodes the longer isoform (a).
- 基因简介:SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列