- accession:NM_001207042
- 基因别名:PRMT1
- 基因描述:Homo sapiens protein arginine methyltransferase 1 (PRMT1), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:858
- 翻译后氨基酸长度:285
- TranscriptVariant:This variant (4) lacks three exons in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
- 基因简介:This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
- 规格:10ul 质粒
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