- accession:NM_001184715
- 基因别名:SLAMF6
- 基因描述:Homo sapiens SLAM family member 6 (SLAMF6), transcript variant 3, mRNA.
- 载体:现货载体
- CDS区长度:849
- 翻译后氨基酸长度:282
- TranscriptVariant:This variant (3) uses multiple alternate splice sites in the coding region, compared to variant 1, which result in an isoform (3) with a shorter extracellular domain than isoform 1.
- 基因简介:The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]
- 规格:10ul 质粒
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