- accession:NM_001243740
- 基因别名:ZNF124
- 基因描述:Homo sapiens zinc finger protein 124 (ZNF124), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:222
- 翻译后氨基酸长度:73
- TranscriptVariant:This variant (2) contains an alternate 3' terminal exon, compared to variant 1, that results in a shorter protein (isoform 2) with a distinct C-terminus that lacks zinc finger domains, compared to isoform 1.
- 基因简介:This gene encodes a member of the Kruppel-type (C2H2) zinc finger protein family. It has a KRAB-A box at its amino terminus and seven consecutively repeated zinc finger motifs at its carboxy terminus. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and its expression inhibits apoptotic cell death induced by irradiation or exposure to etoposide. These attributes suggest that this protein may act as a transcription factor. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described for this gene but their biological validity has not been confirmed. This gene has a pseudogene on chromosome 14. [provided by RefSeq, Aug 2011]
- 规格:10ul 质粒
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