- accession:NM_016953
- 基因别名:PDE11A
- 基因描述:Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 4, mRNA.
- 载体:现货载体
- CDS区长度:2802
- 翻译后氨基酸长度:933
- TranscriptVariant:This variant (4) represents the longest transcript and encodes the longest isoform (4).
- 基因简介:The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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