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人 ABCA1 (NM_005502) cDNA克隆
人 ABCA1 (NM_005502) cDNA克隆
  • 商品货号:FC127195
  • 已售 3 件 | 评价 0 人次 | 关注度 316
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    • accession:NM_005502
    • 基因别名:ABCA1
    • 基因描述:Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1), mRNA.
    • 载体:现货载体
    • CDS区长度:6786
    • 翻译后氨基酸长度:2261
    • 基因简介:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列