×
![]()
- accession：NM_145861
- 基因别名：EDARADD
- 基因描述：Homo sapiens EDAR-associated death domain (EDARADD), transcript variant A, mRNA.
- 载体：现货载体
- CDS区长度：648
- 翻译后氨基酸长度：215
- TranscriptVariant：This variant (A) encodes a longer isoform (A).
- 基因简介：This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
