- accession:NM_004050
- 基因别名:BCL2L2
- 基因描述:Homo sapiens BCL2-like 2 (BCL2L2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:582
- 翻译后氨基酸长度:193
- TranscriptVariant:This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
- 基因简介:This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
- 规格:10ul 质粒
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