- accession:NM_001123396
- 基因别名:CCR2
- 基因描述:Homo sapiens chemokine (C-C motif) receptor 2 (CCR2), transcript variant B, mRNA.
- 载体:现货载体
- CDS区长度:1083
- 翻译后氨基酸长度:360
- TranscriptVariant:This variant (B) differs in the 3' UTR and 3' coding region, compared to variant A. The resulting isoform (B) is shorter and contains a distinct C-terminus, compared to isoform A.
- 基因简介:This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]
- 规格:10ul 质粒
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