- accession:NM_006048
- 基因别名:UBE4B
- 基因描述:Homo sapiens ubiquitination factor E4B (UBE4B), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:3522
- 翻译后氨基酸长度:1173
- TranscriptVariant:This variant (2) lacks an in-frame coding exon in the middle region of the CDS, and thus encodes a shorter isoform (2), as compared to variant 1.
- 基因简介:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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