- accession:NM_001024837
- 基因别名:Adarb1
- 基因描述:Mus musculus adenosine deaminase, RNA-specific, B1 (Adarb1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2136
- 翻译后氨基酸长度:711
- TranscriptVariant:This variant (2) uses an alternate, in-frame donor splice site at one of the internal coding exons, compared to transcript variant 1. This results in a longer isoform (2) containing a 10 aa segment that is missing in isoform 1.
- 基因简介:This gene encodes a double-stranded-RNA-specific adenosine deaminase that is involved in editing pre-mRNAs by site-specific conversion of adenosine (A) to inosine (I). Substrates for this enzyme include ionotropic glutamate receptors (GluR2-6) and serotonin receptor (5HT2C). Studies in rodents have shown that this protein can modify its own pre-mRNA by A->I editing to create a novel acceptor splice site, alternative splicing to which results in down regulation of its protein expression. Additional splicing events result in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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