- accession:NM_010050
- 基因别名:Dio2
- 基因描述:Mus musculus deiodinase, iodothyronine, type II (Dio2), mRNA.
- 载体:现货载体
- CDS区长度:801
- 翻译后氨基酸长度:266
- 基因简介:The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). Knockout studies in mice suggest that this gene may play a role in brown adipose tissue lipogenesis, auditory function, and bone formation. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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