- accession:NM_001271993
- 基因别名:Fut2
- 基因描述:Mus musculus fucosyltransferase 2 (Fut2), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:1044
- 翻译后氨基酸长度:347
- TranscriptVariant:This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
- 基因简介:This gene is one of three genes in mouse which encode a galactoside 2-L-fucosyltransferase. These genes differ in their developmental- and tissue-specific expression. The encoded type II membrane protein is anchored in the Golgi apparatus and controls the final step in the creation of alpha (1,2) fucosylated carbhohydrates by the addition of a terminal fucose in an alpha (1,2) linkage. This enzyme is involved in the synthesis of the Lewis antigen as well as the H-antigen, a precursor of the A and B antigens of the ABH histo-blood group. The biological function of the fucosylated carbhohydrate products is thought to involve cell-adhesion and interactions with microorganisms. Disruption of this gene results in altered glycosylation of gastric mucosa and uterine epithelia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列