- accession:NM_003104
- 基因别名:SORD
- 基因描述:Homo sapiens sorbitol dehydrogenase (SORD), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1074
- 翻译后氨基酸长度:357
- TranscriptVariant:This variant (1) represents the protein-coding transcript.
- 基因简介:Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列