- accession:NM_139171
- 基因别名:STARD6
- 基因描述:Homo sapiens StAR-related lipid transfer (START) domain containing 6 (STARD6), mRNA.
- 载体:现货载体
- CDS区长度:663
- 翻译后氨基酸长度:220
- 基因简介:Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
- 规格:10ul 质粒
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