- accession:NM_010348
- 基因别名:Grik1
- 基因描述:Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:2718
- 翻译后氨基酸长度:905
- TranscriptVariant:This variant (2) is missing an in-frame coding exon at the 3' end compared to transcript variant 1, resulting in a shorter isoform (b) lacking a 29 aa segment compared to isoform a. RNA editing (CAG->CGG) changes Gln621Arg.
- 基因简介:Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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