- accession:NM_001277898
- 基因别名:Prkaca
- 基因描述:Mus musculus protein kinase, cAMP dependent, catalytic, alpha (Prkaca), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1032
- 翻译后氨基酸长度:343
- TranscriptVariant:This variant (2, also known as Cs and Calpha2) contains an alternate 5'-most exon and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct and shorter N-terminus, compared to isoform 1. This variant is testis-specific and the encoded isoform does not contain the myristylation signal found in isoform 1 (PMID: 10841548 and PMID: 10982398). There are no publicly available full-length transcripts for this variant, but it is supported by publication data, including PMID: 10982398.
- 基因简介:This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AMP levels. This gene encodes the alpha catalytic subunit of protein kinase A. Protein kinase A-mediated signaling is transduced via phosphorylation of target proteins, and is important for many cellular functions, including mammalian sperm maturation and motility. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Apr 2013]
- 规格:10ul 质粒
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