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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 小鼠源 > 小鼠 Rp1 (NM_011283) cDNA克隆
小鼠 Rp1 (NM_011283) cDNA克隆
小鼠 Rp1 (NM_011283) cDNA克隆
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    • accession：NM_011283
    • 基因别名：Rp1
    • 基因描述：Mus musculus retinitis pigmentosa 1 (human) (Rp1), transcript variant 1, mRNA.
    • 载体：现货载体
    • CDS区长度：6288
    • 翻译后氨基酸长度：2095
    • TranscriptVariant：This variant (1) encodes the longer isoform (1).
    • 基因简介：This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq, Sep 2010]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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