- accession:NM_001159969
- 基因别名:EPS15
- 基因描述:Homo sapiens epidermal growth factor receptor pathway substrate 15 (EPS15), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1749
- 翻译后氨基酸长度:582
- TranscriptVariant:This variant (2) lacks multiple exons at the 5' end and has a distinct 5' UTR and start codon, compared to variant 1. These differences result in a protein (isoform B) with a shorter and distinct N-terminus, compared to isoform A. Isoform B localizes to early endosome membranes.
- 基因简介:This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列