- accession:NM_001110267
- 基因别名:Vegfa
- 基因描述:Mus musculus vascular endothelial growth factor A (Vegfa), transcript variant 5, mRNA.
- 载体:现货载体
- CDS区长度:342
- 翻译后氨基酸长度:113
- TranscriptVariant:This variant (5) lacks several exons from the 5' end, and an in-frame, internal coding exon, compared to variant 1. This results in a shorter isoform (5) with a different N-terminus, and lacks an internal segment, compared to isoform 1. This variant has transcript support, but the protein is predicted.
- 基因简介:This gene product is a member of the PDGF/VEGF growth factor family. It is a mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Also, alternative translation initiation from non-AUG (CUG) and AUG start sites in some transcript variants, give rise to additional isoforms. The expression of some isoforms derived from AUG start codon is affected by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2013]
- 规格:10ul 质粒
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