- 商品货号:G139155
- accession:NM_009534
- 基因别名:Yap1
- 基因描述:Mus musculus yes-associated protein 1 (Yap1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1419
- 翻译后氨基酸长度:472
- TranscriptVariant:This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded protein (isoform 2) is shorter, compared to isoform 1.
- 基因简介:This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product, a tyrosine kinase. This protein contains a WW domain, consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural, regulatory and signaling molecules in various species, and may play a role in protein-protein interaction. Following cellular damage, phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
- 规格:10ul 质粒
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