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人BAG3(NM_004281)ORF克隆
人BAG3(NM_004281)ORF克隆
  • 商品货号:FO114354
  • 已售 3 件 | 评价 0 人次 | 关注度 382
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    • accession:NM_004281
    • 基因别名:BAG3
    • 基因描述:Homo sapiens BCL2-associated athanogene 3 (BAG3), mRNA.
    • 载体: 现货载体
    • CDS区长度:1728
    • 翻译后氨基酸长度:575
    • 基因简介:BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列