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- accession：NM_001178059
- 基因别名：Txnrd3
- 基因描述：Mus musculus thioredoxin reductase 3 (Txnrd3), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：1617
- 翻译后氨基酸长度：538
- TranscriptVariant：This variant (2) is missing two consecutive internal coding exons compared to variant 1, however, maintains the same reading frame. It can initiate translation from a non-AUG (CUG) start site, and also from an in-frame, downstream AUG. The isoform (3) represented in this RefSeq is derived from the CUG start codon, and lacks an internal protein segment compared to isoform 1.
- 基因简介：This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, but unlike other mammalian thioredoxin reductases (TRs), it contains an additional glutaredoxin domain, and shows highest expression in testes. Like other TRs, it contains a C-terminal, penultimate selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is also evidence for the use of a non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, May 2010]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
