- accession:NM_199478
- 基因别名:PLP1
- 基因描述:Homo sapiens proteolipid protein 1 (PLP1), transcript variant 2, mRNA.
- 载体: 现货载体
- CDS区长度:729
- 翻译后氨基酸长度:242
- TranscriptVariant:This variant (2), also known as DM20, uses an alternate in-frame donor splice site at one of the coding exons compared to transcript variant 1. This results in a shorter isoform (2) missing an internal protein segment compared to isoform 1.
- 基因简介:This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列