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人WNT4(NM_030761)ORF克隆
人WNT4(NM_030761)ORF克隆
  • 商品货号:FO117556
  • 已售 2 件 | 评价 0 人次 | 关注度 359
    • accession:NM_030761
    • 基因别名:WNT4
    • 基因描述:Homo sapiens wingless-type MMTV integration site family, member 4 (WNT4), mRNA.
    • 载体: 现货载体
    • CDS区长度:1056
    • 翻译后氨基酸长度:351
    • 基因简介:The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq, Jul 2008]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列