- accession:NM_000227
- 基因别名:LAMA3
- 基因描述:Homo sapiens laminin, alpha 3 (LAMA3), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:5175
- 翻译后氨基酸长度:1724
- TranscriptVariant:This variant (2) has an alternate 5' end exon and is missing almost half of the coding exons from the 5' end compared to transcript variant 1. This results in a shorter isoform (2) with a distinct N-terminus compared to isoform 1.
- 基因简介:Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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