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- accession：NM_001244937
- 基因别名：MST1R
- 基因描述：Homo sapiens macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：4056
- 翻译后氨基酸长度：1351
- TranscriptVariant：This variant (2) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2, also known as isoform delta-Ron) missing a 49 aa internal protein segment compared to isoform 1. PMID:8816464 reports that this isoform occurs as an uncleaved single-chain protein, is constitutively activated by disulfide-linked intracellular oligomerization, and exhibits an invasive phenotype.
- 基因简介：This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464). [provided by RefSeq, Oct 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
