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- accession：NM_147133
- 基因别名：NFX1
- 基因描述：Homo sapiens nuclear transcription factor, X-box binding 1 (NFX1), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：3075
- 翻译后氨基酸长度：1024
- TranscriptVariant：This variant (2) lacks three 3' terminal exons compared to variant 1 and encodes a shorter isoform (2) with a unique C-terminus.
- 基因简介：MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
