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- accession：NM_004646
- 基因别名：NPHS1
- 基因描述：Homo sapiens nephrosis 1, congenital, Finnish type (nephrin) (NPHS1), mRNA.
- 载体：现货载体
- CDS区长度：3726
- 翻译后氨基酸长度：1241
- 基因简介：This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
