×
![]()
- accession：NM_138323
- 基因别名：PCSK6
- 基因描述：Homo sapiens proprotein convertase subtilisin/kexin type 6 (PCSK6), transcript variant 5, mRNA.
- 载体：现货载体
- CDS区长度：1872
- 翻译后氨基酸长度：623
- TranscriptVariant：This variant (5), also known as PACE4CS, uses an alternate exon in the coding region and 3' UTR, and lacks several downstream exons when compared to variant 1. These differences cause a frameshift and thus isoform e has a distinct C-terminus compared to isoform a. The preproprotein is annotated since the cleavage sites are maintained as in isoform a but this isoform remains in the endoplasmic reticulum as an inactive zymogen.
- 基因简介：The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
