• accession：NM_015725
• 基因别名：RDH8
• 基因描述：Homo sapiens retinol dehydrogenase 8 (all-trans) (RDH8), mRNA.
• 载体：现货载体
• CDS区长度：996
• 翻译后氨基酸长度：331
• 基因简介：All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin (Rando, 2001 [PubMed 11710234]). This is a rate-limiting step in the visual cycle (Saari et al., 1998 [PubMed 9667000]).[supplied by OMIM, Mar 2008]
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGAATGGTCAGAGTCAGGTGCTGCCCGGCGGAGGTCACGAGTCCAGGGAGGGGATCAACATGGCCGCTG
CACCCCGGACTGTGTTGATCTCCGGCTGCTCATCAGGAATTGGTCTGGAACTTGCAGTGCAACTGGCCCA
TGACCCCAAGAAGCGCTACCAGGTCGTGGCCACCATGAGGGACCTGGGGAAGAAGGAGACACTGGAGGCA
GCTGCTGGGGAGGCTCTGGGGCAGACCCTCACCGTGGCCCAGCTGGACGTGTGCAGTGATGAGTCGGTGG
CCCAGTGTCTCAGCTGTATCCAGGGAGAAGTGGACGTGCTGGTGAATAATGCTGGAATGGGCCTGGTGGG
GCCCCTGGAGGGGCTCAGCCTTGCTGCCATGCAGAATGTCTTTGACACCAACTTTTTCGGAGCTGTCCGT
CTCGTCAAAGCTGTGCTTCCAGGCATGAAGAGGAGGCGGCAGGGCCACATCGTGGTGATCAGCAGTGTCA
TGGGCCTGCAGGGTGTCATCTTCAACGATGTCTATGCAGCTTCCAAGTTCGCCCTGGAGGGATTCTTCGA
AAGCCTCGCTATCCAGCTGCTGCAGTTCAACATCTTCATCTCCCTGGTGGAGCCAGGCCCCGTGGTCACC
GAGTTTGAGGGGAAGCTTCTGGCGCAGGTTTCTATGGCTGAGTTCCCAGGCACTGACCCTGAGACCCTGC
ACTACTTCCGGGACCTCTATCTCCCAGCCTCCAGGAAGCTGTTTTGCTCCGTGGGACAGAACCCACAGGA
CGTGGTTCAGGCCATTGTCAACGTCATCAGCTCGACTCGACCACCCCTGCGCCGACAGACCAACATCCGC
TACTCGCCGCTGACCACGCTCAAAACCGTGGATTCCTCTGGCAGCCTGTATGTGCGAACGACCCACCGCC
TCCTCTTCCGCTGTCCACGCCTCCTCAACCTTGGCCTTCAATGTCTGTCCTGCGGCTGCCTCCCAACGCG
GGTGCGGCCAAGATGA

翻译后氨基酸参数序列： 点击查看序列

ATGAATGGTCAGAGTCAGGTGCTGCCCGGCGGAGGTCACGAGTCCAGGGAGGGGATCAACATGGCCGCTG
CACCCCGGACTGTGTTGATCTCCGGCTGCTCATCAGGAATTGGTCTGGAACTTGCAGTGCAACTGGCCCA
TGACCCCAAGAAGCGCTACCAGGTCGTGGCCACCATGAGGGACCTGGGGAAGAAGGAGACACTGGAGGCA
GCTGCTGGGGAGGCTCTGGGGCAGACCCTCACCGTGGCCCAGCTGGACGTGTGCAGTGATGAGTCGGTGG
CCCAGTGTCTCAGCTGTATCCAGGGAGAAGTGGACGTGCTGGTGAATAATGCTGGAATGGGCCTGGTGGG
GCCCCTGGAGGGGCTCAGCCTTGCTGCCATGCAGAATGTCTTTGACACCAACTTTTTCGGAGCTGTCCGT
CTCGTCAAAGCTGTGCTTCCAGGCATGAAGAGGAGGCGGCAGGGCCACATCGTGGTGATCAGCAGTGTCA
TGGGCCTGCAGGGTGTCATCTTCAACGATGTCTATGCAGCTTCCAAGTTCGCCCTGGAGGGATTCTTCGA
AAGCCTCGCTATCCAGCTGCTGCAGTTCAACATCTTCATCTCCCTGGTGGAGCCAGGCCCCGTGGTCACC
GAGTTTGAGGGGAAGCTTCTGGCGCAGGTTTCTATGGCTGAGTTCCCAGGCACTGACCCTGAGACCCTGC
ACTACTTCCGGGACCTCTATCTCCCAGCCTCCAGGAAGCTGTTTTGCTCCGTGGGACAGAACCCACAGGA
CGTGGTTCAGGCCATTGTCAACGTCATCAGCTCGACTCGACCACCCCTGCGCCGACAGACCAACATCCGC
TACTCGCCGCTGACCACGCTCAAAACCGTGGATTCCTCTGGCAGCCTGTATGTGCGAACGACCCACCGCC
TCCTCTTCCGCTGTCCACGCCTCCTCAACCTTGGCCTTCAATGTCTGTCCTGCGGCTGCCTCCCAACGCG
GGTGCGGCCAAGATGA