- accession:NM_000278
- 基因别名:PAX2
- 基因描述:Homo sapiens paired box 2 (PAX2), transcript variant b, mRNA.
- 载体:现货载体
- CDS区长度:1182
- 翻译后氨基酸长度:393
- TranscriptVariant:This variant (b) lacks an alternate in-frame exon and uses an alternate splice site in the 3' coding region, compared to variant e. This results in a protein (isoform b) with a shorter, distinct C-terminus compared to isoform e.
- 基因简介:PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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