- accession:NM_016363
- 基因别名:GP6
- 基因描述:Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1020
- 翻译后氨基酸长度:339
- TranscriptVariant:This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform 2 which has a shorter and distinct C-terminus compared to isoform 1.
- 基因简介:This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- 规格:10ul 质粒
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