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- accession：NM_001037339
- 基因别名：PDE4B
- 基因描述：Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant b, mRNA.
- 载体：现货载体
- CDS区长度：1695
- 翻译后氨基酸长度：564
- TranscriptVariant：This variant (b) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant a. The resulting isoform (2, also referred to as PDE4B2 or PDE32) has a shorter and distinct N-terminus when compared to isoform 1.
- 基因简介：This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
