- accession:NM_000880
- 基因别名:IL7
- 基因描述:Homo sapiens interleukin 7 (IL7), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:534
- 翻译后氨基酸长度:177
- TranscriptVariant:This variant (1) represents the longest transcript and encodes the longest isoform (1).
- 基因简介:The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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