- accession:NM_207111
- 基因别名:RNF216
- 基因描述:Homo sapiens ring finger protein 216 (RNF216), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2772
- 翻译后氨基酸长度:923
- TranscriptVariant:This variant (1, also known as TRIAD3B) represents the longer transcript and it encodes the longer isoform (a).
- 基因简介:This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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