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- accession：NM_001135597
- 基因别名：CCDC88A
- 基因描述：Homo sapiens coiled-coil domain containing 88A (CCDC88A), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：5613
- 翻译后氨基酸长度：1870
- TranscriptVariant：This variant (1) represents the longest transcript and encodes the longest isoform (1).
- 基因简介：This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
