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人 ZP4 (NM_021186) cDNA克隆
人 ZP4 (NM_021186) cDNA克隆
  • 商品货号:FC158715
  • 已售 4 件 | 评价 0 人次 | 关注度 354
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    • accession:NM_021186
    • 基因别名:ZP4
    • 基因描述:Homo sapiens zona pellucida glycoprotein 4 (ZP4), mRNA.
    • 载体:现货载体
    • CDS区长度:1623
    • 翻译后氨基酸长度:540
    • 基因简介:The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列