- accession:NM_001706
- 基因别名:BCL6
- 基因描述:Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:2121
- 翻译后氨基酸长度:706
- TranscriptVariant:This variant (1) and variant 2 encode the same isoform (1).
- 基因简介:The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列