- accession:NM_022162
- 基因别名:NOD2
- 基因描述:Homo sapiens nucleotide-binding oligomerization domain containing 2 (NOD2), mRNA.
- 载体:现货载体
- CDS区长度:3123
- 翻译后氨基酸长度:1040
- 基因简介:This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列