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- accession：NM_001128849
- 基因别名：SMARCA4
- 基因描述：Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：5040
- 翻译后氨基酸长度：1679
- TranscriptVariant：This variant (1) encodes the longest isoform (A, also known as 2). There are no publicly available full-length transcripts representing the exon combination of this variant; it is based on mRNA annotation on DNA accession AF254822.1, which is derived from data in PMID:11085541.
- 基因简介：The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
