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人ACE2(NM_021804)ORF克隆 CALU-3细胞 vero E6非洲绿猴肾细胞
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当前位置: 首页 > 质粒载体菌株 > cDNA克隆 > 人源 > 人 ARID1A (NM_006015) cDNA克隆
人 ARID1A (NM_006015) cDNA克隆
人 ARID1A (NM_006015) cDNA克隆
  • 商品货号：FC172450
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    • accession：NM_006015
    • 基因别名：ARID1A
    • 基因描述：Homo sapiens AT rich interactive domain 1A (SWI-like) (ARID1A), transcript variant 1, mRNA.
    • 载体：现货载体
    • CDS区长度：6858
    • 翻译后氨基酸长度：2285
    • TranscriptVariant：This variant (1) is the longer transcript and encodes the longer isoform (a).
    • 基因简介：This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    • 规格：10ul 质粒
    CDS区参考序列： 点击查看序列
    翻译后氨基酸参数序列： 点击查看序列
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